A pilonidal cyst is a spherical sac of tissue containing air or fluid. This common type of cyst is seen in the buttock crease and is usually caused by a skin infection. A pilonidal cyst is a spherical sac of tissue containing air or fluid. This common type of cyst is seen in the buttock crease and is usually caused by a skin infection. Pilonidal cysts are a somewhat common condition. Pilonidal cysts can be painful and must be treated. Pilonidal cysts can be a one-time (acute) condition or chronic (reoccurring). Chronic pilonidal cysts, if left untreated, can lead to abscesses (swollen pockets of infection) and sinus cavities (empty spaces beneath the skin). A pilonidal cyst (also known as pilonidal cyst disease, intergluteal pilonidal disease, or pilonidal sinus) is a skin ailment that occurs in the buttock crease, ranging from the tailbone to the anus. A pilonidal cyst can be excruciatingly uncomfortable, particularly when sitting.
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